ea0073aep507 | Pituitary and Neuroendocrinology | ECE2021
Nanna Jørgensen
, Erichsen Trine
, Klose Marianne
, Joergensen Morten
, Idorn Thomas
, Feldt-Rasmussen Bo
, Holst Jens J.
, Feldt-Rasmussen Ulla
ContextActive acromegaly is associated with impaired glucose metabolism, which improves upon treatment. Treatment options include surgery, medical therapy with somatostatin analogues (SSA) and Pegvisomant (PEG) and in few cases irradiation.ObjectiveTo describe the differential effect of various treatment regimens on the secretion of glucose, insulin, glucagon, glucagon-like peptide-1 (GLP1), and glucose-depen...